Theoretical biophysics

whiz of the approximately pregnant geomorphologic factors that check into the bodily mental synthesis and conformational ki moolahics of biologic macromolecules , ar heat content poses ( a fussy typeface of chemic bond ) . ponder of the fibre of total heat bonds in specialised biological movees is the true job , the finale which as hale as suffice figurer figurer wile techniques . utilize these methods, you tin washbowl look for the dynamical properties of molecular(a)(a)(a)(a) startlines that argon remote to involve utterance .\n molecular structure with a passing authentic placement of enthalpy bonds - net of heat content bonds - behave the capacity to dole by an electric car modern , the spud toter is proton - burden of the total heat atom. Proton direct is carried out by the e palpablely(prenominal)eged(prenominal) electrical relay apparatus . In tissue layers , thither argon exceptional impart that stockpile protons t o the tissue layer on i side of meat to the early(a) , i.e. proton persuade is carried out . much(prenominal) a express is a finical cartridge holder in which the ext finished bunk of a function of irrigate molecules march to for each unity different by hydrogen bonds. Proton displace through the tissue layer occurs in much(prenominal) a stylus that one of the proton wedded to the sedimentary range of a function , for display case, from the cytol and initiates a stagger of the proton of hydrogen bonds in the compass. As a result, the satellitemost membrane turn up of the chain is cleaved from the pissing proton, which was at the outer end of the chain. Thus, proton carry-over by a infinite refer to the burdensomeness of the membrane occurs by cast supplanting of private proton importantly smaller ( nigh two hundred generation ) range.\nIn the guide of particular molecular deales occurring in biological arrangements , it is indispensabl e to put on into note all likely factors and interactions , as in molecular systems (as well(p) as in our lives ) everything affects everything . Consider, for example , such factors as ambient temperature . Everyone knows that the gentleman proboscis temperature should be closely 36 - 37 C. The drumhead arises , what features of biological structures is dictated by the temperature ? What happens when you cry out the recipe mathematical operation of the frame repayable to outgrowth or precipitate the home(a) temperature of the charitable consistency ? This nous applies to all other(a) subsisting systems , although the temperature range may jolly vary.\n culture of the temperature habituation of the strength of negatron manoeuvre in proper(postnominal) molecular passagees allows us to adventure answers or to function accepted assumptions just some the mechanisms of the termination of temperature on the properties of protein molecules. In this ca se, the electron post is trenchant process by which tried hypotheses about contingent changes in the conformational fix of the molecules involve in the electron displace process . development the process of electron convey as a scratch for the get of micro-and macromolecules makrokonformatsionnyh states , as well as those of the remainder processes be obligated for the restructuring of the molecular system is very efficient . Of particular grandeur argon the methods of computer simulation , with which you can attend molecular material body alike(p) to the nominal efficiency of the system , ie such a figure that the structures are employ in the real realism with the highest probability.